Rejuran is an injectable treatment that uses polynucleotides, naturally occurring DNA fragments derived from salmon, to stimulate the skin’s repair processes at a cellular level. Unlike fillers that add volume or toxins that relax muscles, Rejuran works by promoting collagen production and cellular renewal to address fine lines, uneven texture, and reduced elasticity while providing deep hydration.
Rejuran contains fragments of DNA molecules extracted and purified from salmon, which are highly compatible with human tissue. When injected into the skin, these compounds stimulate the cells that produce collagen and other structural proteins. It enhances cell function, promotes the formation of new blood vessels for improved circulation and nutrient delivery, reduces inflammation, and attracts moisture for deep hydration.
Unlike fillers or neurotoxins, Rejuran works at a cellular level to improve tissue quality by stimulating the skin’s own repair processes, gradually restoring healthier function and appearance over time.
Rejuran contains fragments of DNA molecules extracted and purified from salmon, which are highly compatible with human tissue. When injected into the skin, these compounds stimulate the cells that produce collagen and other structural proteins. It enhances cell function, promotes the formation of new blood vessels for improved circulation and nutrient delivery, reduces inflammation, and attracts moisture for deep hydration.
Unlike fillers or neurotoxins, Rejuran works at a cellular level to improve tissue quality by stimulating the skin’s own repair processes, gradually restoring healthier function and appearance over time.
Rejuran addresses multiple aspects of skin ageing and damage by working at a cellular level to stimulate the skin’s natural repair mechanisms. Because it promotes fundamental processes like collagen synthesis and tissue regeneration rather than targeting single concerns, it can improve overall skin quality across several areas simultaneously. Rejuran is effective for:
Rejuran offers benefits from improving skin texture and elasticity to reducing fine lines and restoring hydration. Before recommending treatment, we take time to understand what you hope to achieve and how Rejuran might fit into your skincare goals. This helps us determine the appropriate treatment protocol and number of sessions for your skin.
Rejuran works by delivering polynucleotides that support your skin’s natural repair processes and encourage tissue regeneration. This helps improve overall skin health from within rather than just addressing surface concerns.
The treatment can help reduce the appearance of fine lines, enlarged pores, and rough texture while improving skin elasticity and hydration. Many people notice their skin feels smoother, plumper, and more resilient after treatment.
Rejuran may help improve the appearance of acne scars by promoting collagen remodelling and supporting the skin’s healing response. This makes it valuable for people struggling with textural scarring from previous breakouts.
Results from Rejuran develop gradually and can last several months as your skin continues to benefit from improved healing capacity and structural support. Regular treatments can help maintain and build upon these improvements over time.
Rejuran works well alongside other skin treatments and can be incorporated into a comprehensive skincare approach. It may enhance results when combined with procedures that address different aspects of skin ageing or damage.
The treatment is generally well-tolerated, even by people with sensitive or reactive skin who may not be able to tolerate more aggressive procedures. It works gently to support skin health without causing significant inflammation.
While there may be some initial redness and small bumps at injection sites, recovery is relatively quick compared to more intensive treatments. Most people can resume normal activities within a day or two.
We begin by assessing your skin to determine if Rejuran is the right approach for your concerns. We’ll discuss the treatment process, expected results, and how many sessions you may need.
On treatment day, we apply topical anaesthetic cream to ensure your comfort. Once the area is numb, we systematically inject small amounts of Rejuran beneath the skin’s surface using very fine needles. The injection pattern creates multiple tiny deposits throughout the tissue for widespread distribution. Treatment typically takes twenty to thirty minutes for full-face application.
Immediately after treatment, you’ll notice small injection marks, mild swelling, and possibly slight redness. These effects are normal and typically settle within hours to a day or two. Results develop gradually over several weeks as the polynucleotides stimulate collagen production and cellular renewal, with optimal improvement visible after a series of treatments.
If you’re noticing signs of skin ageing, loss of vitality, or sun damage, or wish to improve your skin’s overall quality, book a consultation at South Yarra Dermatology to discuss whether Rejuran is right for you.
Rejuran and dermal fillers work in fundamentally different ways. Fillers add volume beneath the skin to plump areas and fill lines, with results you can see immediately. Rejuran takes a different approach. It stimulates your skin’s own repair processes to improve tissue quality from within. Results develop gradually over weeks to months as your cells are activated.
While fillers change contour and add volume, Rejuran improves overall skin quality, texture, and hydration. Many people find both treatments helpful for different reasons, and they can work well together.
Rejuran is similar to other injectable skin boosters in how it’s administered, but what’s inside is different. Most skin boosters contain hyaluronic acid, which provides hydration by attracting and holding moisture. Rejuran contains polynucleotides (fragments of DNA molecules) that work by stimulating your cells to function better.
Both involve multiple small injections across treatment areas, but they achieve their results through different pathways. We can help you decide which option, or combination, would work best for your skin.
We want you to be comfortable during treatment, so we apply topical numbing cream beforehand. Most people find the procedure quite manageable with this preparation. You’ll likely feel some pressure with each injection and possibly mild stinging, particularly in more sensitive areas, but these sensations are brief.
Because the treatment involves many small injections, the experience can become a bit more noticeable toward the end, though individual tolerance varies. Some people report minimal discomfort, while others find it slightly more challenging. After treatment, you may feel some tenderness for a day or two, but this is typically mild and temporary.
Plan for about sixty to ninety minutes for your appointment. Most of this time is for the numbing cream to take effect (thirty to forty-five minutes), while the actual treatment takes about twenty to thirty minutes. We also allow time to discuss your treatment and answer any questions.
If you’re having multiple areas treated or combining treatments, your appointment will be longer. We want to ensure you’re not rushed and that you’re completely comfortable throughout.
Right after treatment, you’ll see small injection marks across the treated areas, such as tiny dots or bumps where each injection was placed. Some swelling is normal, especially in areas with thinner skin, along with mild redness around injection sites. Occasionally, you might notice minor bruising. The area may feel slightly tender to the touch.
Your skin will show that you’ve had treatment, though most people feel comfortable going about their day. These effects typically start settling within hours and are mostly gone within one to two days. You can apply makeup the next day if you’d like to camouflage any remaining marks.
Recovery is quite minimal. Most visible effects settle within one to two days. The injection marks usually flatten within hours to a day, and any swelling typically resolves within a day or two. Redness often settles within hours. If you do get some bruising, it may last several days but it can be easily covered with makeup.
Most people return to work and their usual activities right away. Within two to three days, you should look essentially back to normal, perhaps with just slight tenderness remaining.
Results appear gradually, which is different from some other treatments. You might notice subtle improvements like better hydration or smoother texture within two to three weeks after your first session, though these early changes are often modest.
More noticeable results typically become apparent after you complete your initial series of three to four treatments, usually around eight to twelve weeks from when you start. Your results will continue improving even after your final session as your collagen production increases and your cells continue regenerating.
The full effect usually becomes most apparent several months after completing your series. We know it requires patience, but the improvements are genuine and develop naturally over time.
Results typically last several months to over a year after you complete your initial series, though this varies from person to person. How long your results last depends on factors like your age and skin condition, how well you protect your skin from the sun and care for it, your lifestyle habits, and your individual biology.
The improvements you achieve are real enhancements to your tissue quality, but your skin will continue aging naturally. Most people find that maintenance treatments once or twice a year help sustain their results. With good skincare habits and periodic maintenance, you can maintain improved skin quality over the long term.
Yes, we typically recommend multiple sessions spaced two to four weeks apart. This approach allows the benefits to build progressively as each treatment stimulates your cellular processes. While a single treatment may provide some benefit, completing the full series gives you the best chance of meaningful, lasting improvement.
After your initial series, maintenance treatments help preserve your results. We usually suggest these every six to twelve months, depending on how your skin responds and how long your results last.
Yes, one of Rejuran’s advantages is that it works well across all skin types, including darker skin tones that may have higher risk with some other treatments. Because Rejuran stimulates your cells rather than using heat or other mechanisms that can affect pigmentation, it’s generally tolerable for diverse complexions. It won’t cause the pigmentation changes that some people with darker skin worry about with certain procedures.
That said, everyone’s skin heals a bit differently, and bruising or injection marks may be more visible or last longer in some people. We use careful technique to ensure optimal results for your individual skin type.
If you have a known allergy to salmon or seafood, we’ll need to discuss this carefully, though the purified form used in Rejuran may not cause reactions. We typically postpone treatment if you’re pregnant or breastfeeding. If you have active skin infections or inflammation, we’ll wait until these resolve.
Autoimmune conditions or immune system disorders need careful consideration, often in consultation with your other physicians. Blood clotting disorders or blood-thinning medications increase bruising risk, so we’ll need to assess this. If you have a history of excessive scarring or keloid formation, we should discuss this.
Yes, Rejuran often works well alongside other treatments as part of a comprehensive approach to skin rejuvenation. It can be paired with neurotoxins for wrinkle reduction, dermal fillers for volume restoration, lasers for pigmentation or texture concerns, chemical peels for surface improvement, or microneedling and radiofrequency for additional collagen stimulation.
However, we don’t typically perform treatments on the same day. Spacing them out allows each to settle independently and prevents overwhelming your skin. The specific timing depends on which treatments you’re combining. During your consultation, we’ll develop a coordinated plan that works for your goals.
